URSOSAN 50 tabs, 250 mg
Active component: Ursodeoxycholic acid
Form release: 50 tabs, 250 mg
Manufacturer: Czech Republic, Pro.Med.Cs Praha AS
Dosage form: capsules, oral suspension
Pharmacological properties of the drug UROSAN:
Ursodeoxycholic acid after insertion into the membrane of hepatocytes, it helps stabilize the structure protects hepatic cells, induces cholepoiesis rich bicarbonates; inhibits absorption of lipophilic bile acids in the intestine.
INDICATIONS FOR DRUG UROSAN:
Ursosan has these effects:
hepatoprotective (liver cell membrane stabilizes and increases the resistance to damaging factors);
anticholestatic and choleretic (increases the passage of bile and excretion of toxic bile acids through the intestines);
immunomodulatory (reduce autoantibody production and reduces immunopathological reactions);
litholytic (dissolves cholesterol stones and prevents the formation of new ones);
cholesterol-lowering (decreases the saturation of bile with cholesterol due to inhibition of its absorption in the intestine, suppression of synthesis in the liver and reduce the secretion into bile);
antiapoptotic (reduces programmed cell death of the liver);
antifibrotic (reduces synthesis of connective tissue in the liver).
The duration of treatment :
chronic viral hepatitis types B and C - daily for 2-6 months;
cholelithiasis - daily for 8-18 months;
chronic cholestatic liver disease (primary sclerosing cholangitis, primary biliary cirrhosis) - daily for 2-3 years or more.
Thus, the average dose - 10-15 mg / kg (2-3 capsules) per day, and duration of treatment of chronic diseases of the hepatobiliary system - from 2 months to several years, and to achieve an optimal result is important continuity and duration of treatment .
Ursosan almost shows no side effects, so it can be used over a long period in adults and in children under the age of 3 years. This is especially important because the treatment of primary sclerosing cholangitis and primary biliary cirrhosis - life.